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  <titleInfo>
    <title>Forward-Time Population Genetics Simulations : Methods, Implementation, and Applications</title>
  </titleInfo>
  <name type="personal">
    <namePart>Peng, Bo</namePart>
    <namePart type="date">1974-</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Kimmel, Marek</namePart>
    <namePart type="date">1959-</namePart>
  </name>
  <name type="personal">
    <namePart>Amos, Christopher I.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
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  <genre authority="">Electronic books.</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
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      <placeTerm type="code" authority="marccountry">nju</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
    </place>
    <publisher>Wiley Blackwell</publisher>
    <dateIssued>©2012</dateIssued>
    <dateIssued encoding="marc">2012</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
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    <extent>1 online resource (xxi, 234 pages) : illustrations</extent>
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  <abstract>The rapid increase of the power of personal computers has led to the use of serious simulation programs such as easy POP in genetic studies. This book summarizes recent advances in forward-time simulation methods and demonstrates their applications in population genetics and genetic epidemiology. The authors introduce commonly used forward-time population genetics simulation methods, including some new methods, and introduce a forward-time population genetics simulation environment, simuPOP, as a powerful and flexible tool to implement these simulations. Researchers and students in population and statistical genetics will find this book useful.</abstract>
  <tableOfContents>Frontmatter -- Basic Concepts and Models -- Simulation of Population Genetics Models -- Ascertainment Bias in Population Genetics -- Observing Properties of Evolving Populations -- Simulating Populations with Complex Human Diseases -- Nonrandom Mating and its Applications -- Appendix: Forward-Time Simulations Using simuPOP -- Index.</tableOfContents>
  <tableOfContents>Basic concepts and models -- Simulation of population genetics models -- Ascertainment bias in population genetics -- Observing properties of evolving populations -- Simulating populations with complex human diseases -- Nonrandom mating and its applications.</tableOfContents>
  <note type="statement of responsibility">Bo Peng, Marek Kimmel, Christopher I. Amos.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Population genetics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Evolution (Biology)</topic>
    <topic>Computer simulation</topic>
  </subject>
  <subject authority="mesh">
    <topic>Genetics, Population</topic>
  </subject>
  <subject authority="mesh">
    <topic>Biological Evolution</topic>
  </subject>
  <subject authority="mesh">
    <topic>Computer Simulation</topic>
  </subject>
  <subject authority="mesh">
    <topic>Models, Genetic</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>SCIENCE</topic>
    <topic>Life Sciences</topic>
    <topic>Genetics &amp; Genomics</topic>
  </subject>
  <subject authority="fast">
    <topic>Evolution (Biology)</topic>
    <topic>Computer simulation</topic>
  </subject>
  <subject authority="fast">
    <topic>Population genetics</topic>
  </subject>
  <classification authority="lcc">QH455 .P464 2012eb</classification>
  <classification authority="ddc" edition="23">576.5/8</classification>
  <classification authority="nlm">QU 450</classification>
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      <title>Forward-time population genetics simulations</title>
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    <name>
      <namePart>Peng, Bo, 1974-</namePart>
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    <originInfo>
      <publisher>Hoboken, N.J. : Wiley Blackwell, ©2012</publisher>
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    <identifier type="local">(DLC)  2011033593</identifier>
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  <identifier type="isbn">9781118180327</identifier>
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  <identifier type="isbn">9781118180358</identifier>
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  <identifier type="stock number">10.1002/9781118180358 Wiley InterScience</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781118180358</identifier>
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    <recordCreationDate encoding="marc">110809</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171115082405.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn785782715</recordIdentifier>
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