05383cam a2200817 i 4500 ocn779097306 OCoLC 20171115102837.0 m o d cr ||||||||||| 120302s2012 nju ob 001 0 eng 2012009479 9781118347331 (ePub) 1118347331 (ePub) 9781118347317 (MobiPocket) 1118347315 (MobiPocket) 9781118347324 (Adobe PDF) 1118347323 (Adobe PDF) 9781118347300 (electronic bk.) 1118347307 (electronic bk.) 1119976685 9781119976684 1119976693 9781119976691 9781280775710 (MyiLibrary) 1280775718 (MyiLibrary) 9781118087206 (pbk. ; acid-free paper) AU@ 000053010239 DEBSZ 372597289 DEBSZ 431152470 DKDLA 820120-katalog:000610131 NLGGC 343625911 NZ1 14690869 NZ1 15024353 NZ1 15340833 NZ1 16094344 DEBSZ 463011767 DEBBG BV041828979 (OCoLC)779097306 (OCoLC)802045890 (OCoLC)927507651 (OCoLC)966211976 DLC eng rda pn DLC EBLCP N$T DG1 MERUC OCLCF YDXCP E7B DEBSZ CDX COO OCLCQ DG1 LOA pcc MAIN QD415 SCI 013040 bisacsh 547/.2 23 SCI013040 bisacsh Koskinen, Ari. Asymmetric synthesis of natural products / Ari M.P. Koskinen, Department of Chemistry, Aalto University, School of Chemical Technology, Espoo, Finland. [electronic resource] Second edition. Chichester, West Sussex, United Kingdom : Wiley, 2012. 1 online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Asymmetric Synthesis of Natural Products; Contents; Preface to the First Edition; Preface to the Second Edition; List of Common Abbreviations; Chapter 1 Introduction; 1.1 Some properties of natural products; 1.2 Natural products as drugs; 1.3 Structures of natural products; 1.4 Asymmetric synthesis of natural products; 1.5 Synthetic organic chemistry; References; Chapter 2 Chirality, Topology, and Asymmetric Synthesis; 2.1 The need for enantiopure compounds; 2.2 Determination of enantiomeric purity; 2.3 Chirality and thermodynamic principles of asymmetric induction. "Natural product synthesis has played a key role in the development of many synthetic methods and will continue to do so in the future. Many recent advances in such diverse fields as immunology, cellular biology and materials science have been achieved through the synthetic chemist's ability to construct often very complicated structures in one enantiomeric form. Asymmetric Synthesis of Natural Products, 2nd Edition introduces students to this rapidly growing field of organic chemistry. The initial chapters present the foundations of asymmetric synthesis, including the theory and applications of individual asymmetric reactions. This is followed by chapters on each of the major individual classes of natural products; their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds. Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikamic acid derivatives and alkaloids. For this second edition the text has been thoroughly updated and expanded, and includes new discussions and examples covering atom and redox economies, practical aspects and environmental awareness. Organocatalysis has emerged completely in the last ten years, and has been fully integrated into this new edition. Asymmetric Synthesis of Natural Products, 2nd Edition will find a place on the bookshelves of advanced undergraduates and postgraduates working in natural products chemistry, organic synthesis, medicinal chemistry and drug discovery. It is also useful for practising researchers who want to refresh their knowledge of the field"-- Provided by publisher. "Based on a successful course taught for the last 20 years at universities in the UK, Finland and elsewhere"-- Provided by publisher. Print version record and CIP data provided by publisher. Natural products Synthesis. Asymmetry (Chemistry) SCIENCE Chemistry Organic. bisacsh Asymmetry (Chemistry) fast (OCoLC)fst00819863 Natural products Synthesis. fast (OCoLC)fst01034399 Electronic books. Electronic books. Electronic books. local Print version: Koskinen, Ari. Asymmetric synthesis of natural products. Second edition. Hoboken, New Jersey : Wiley, 2012 9781118087206 (DLC) 2012008652 http://onlinelibrary.wiley.com/book/10.1002/9781118347300 Wiley Online Library ddc BK 205663 205663