<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.1" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
  <titleInfo>
    <title>Molecular analysis and genome discovery</title>
  </titleInfo>
  <name type="personal">
    <namePart>Rapley, Ralph.</namePart>
  </name>
  <name type="personal">
    <namePart>Harbron, Stuart.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <genre authority="">Electronic resource.</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">enk</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Chichester, West Sussex</placeTerm>
    </place>
    <publisher>John Wiley &amp; Sons</publisher>
    <dateIssued>2011</dateIssued>
    <edition>2nd ed.</edition>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>1 online resource</extent>
  </physicalDescription>
  <abstract>Molecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and developed. Each chapter offers an up-to-date analysis of the subject encompassing the very latest technology platforms and is an essential reference for researchers in the field looking for an up-to-date overview of the subject. The book will also be an indispensable resource for those working in the biotechnology and pharmaceutical industries. New for this edition: chapters on Genotyping through Mutation Detection; Differential Gene Expression; Haplotyping and Molecular Profiling.</abstract>
  <tableOfContents>Front Matter -- Overview of Genotyping / Monica Bayes, Ivo Glynne Gut -- DNA Chip Analysis in Genome Discovery / Ross N Nazar, Jane Robb -- qPCR, Theory, Reliability and Use in Molecular Analysis / Jamie Murphy, Stephen A Bustin -- DNA Analysis in Droplet-Based Microfluidic Devices / Pinar Ozdemir, Yonghao Zhang -- High-Resolution Melt Profiling / Steven F Dobrowolski, Carl T Wittwer -- Massively Parallel Sequencing / Tracy Tucker, Marco Marra, Jan M Friedman -- Aptamers for Analysis: Nucleic Acids Ligands in the Post-Genomic Era / Pedro Nadal, Alessandro Pinto, Marketa Svobodova, Ciara K O'sullivan -- Use of Nanotechnology for Enhancing of Cancer Biomarker Discovery and Analysis: A Molecular Approach / Farid E Ahmed -- Chip-Based Proteomics / Julian Bailes, Andrew Milnthorpe, Sandra Smieszek, Mikhail Soloviev -- Antibody Microarrays in Proteome Profiling / Mohamed Saiel Saeed Alhamdani, Jorg D Hoheisel -- Biomarker Detection and Molecular Profiling by Multiplex Microbead Suspension Array Based Immunoproteomics / V V Krishhan, Imran H Khan, Paul A Luciw -- Mass Spectrometry in Metabolomics / William J Griffiths, Yuqin Wang -- Index.</tableOfContents>
  <note type="statement of responsibility">edited by Ralph Rapley and Stuart Harbron.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Molecular diagnosis</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Genomics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Proteomics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Pharmacogenomics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Polymerase chain reaction</topic>
  </subject>
  <subject authority="lcsh">
    <topic>DNA microarrays</topic>
  </subject>
  <subject authority="mesh">
    <topic>Genomics</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Design</topic>
  </subject>
  <subject authority="mesh">
    <topic>Genetic Techniques</topic>
  </subject>
  <subject authority="mesh">
    <topic>Metabolomics</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Proteomics</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="fast">
    <topic>DNA microarrays</topic>
  </subject>
  <subject authority="fast">
    <topic>Genomics</topic>
  </subject>
  <subject authority="fast">
    <topic>Molecular diagnosis</topic>
  </subject>
  <subject authority="fast">
    <topic>Pharmacogenomics</topic>
  </subject>
  <subject authority="fast">
    <topic>Polymerase chain reaction</topic>
  </subject>
  <subject authority="fast">
    <topic>Proteomics</topic>
  </subject>
  <classification authority="lcc">RB43.7 .M595 2011eb</classification>
  <classification authority="ddc" edition="23">615/.7</classification>
  <classification authority="nlm">QU 58.5</classification>
  <relatedItem type="otherFormat" displayLabel="Print version:">
    <identifier type="local">(DLC)  2011019770</identifier>
  </relatedItem>
  <identifier type="isbn">0470758775</identifier>
  <identifier type="isbn">9780470758779</identifier>
  <identifier type="isbn">9781119977438</identifier>
  <identifier type="isbn">1119977436</identifier>
  <identifier type="isbn">9781119977445</identifier>
  <identifier type="isbn">1119977444</identifier>
  <identifier type="lccn" invalid="yes"/>
  <identifier type="stock number">328453 MIL</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781119977438</identifier>
  <location>
    <url>http://onlinelibrary.wiley.com/book/10.1002/9781119977438</url>
  </location>
  <recordInfo>
    <recordContentSource authority="marcorg">CDX</recordContentSource>
    <recordCreationDate encoding="marc">110509</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171116092531.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn767579263</recordIdentifier>
    <languageOfCataloging>
      <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
    </languageOfCataloging>
  </recordInfo>
</mods>
