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  <titleInfo>
    <title>Neurodegeneration : the molecular pathology of dementia and movement disorders</title>
  </titleInfo>
  <name type="personal">
    <namePart>Dickson, Dennis.</namePart>
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  <genre authority="">Electronic books.</genre>
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    <place>
      <placeTerm type="text">Chichester, West Sussex</placeTerm>
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    <publisher>Wiley-Blackwell</publisher>
    <dateIssued>2011</dateIssued>
    <edition>2nd ed.</edition>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
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    <extent>1 online resource (xvii, 477 pages) : illustrations (some color)</extent>
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  <abstract>Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology.℗¡ In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries.℗¡ Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells.</abstract>
  <tableOfContents>Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders; Contents; List of Contributors; Preface; List of Abbreviations; Part 1: Introduction: Basic Mechanisms of Neurodegeneration; 1: Introduction to Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders; 2: Cell Death and Neurodegeneration; 3: Oxidative Stress and Balance in Neurodegenerative Diseases; 4: Protein Aggregation in Neurodegeneration; 5: Protein Degradation in Neurodegeneration: The Ubiquitin Pathway; 6: Genetics of Neurodegeneration; 7: Transgenic Animal Models of Proteinopathies.</tableOfContents>
  <note type="statement of responsibility">edited by Dennis W. Dickson.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Nervous system</topic>
    <topic>Degeneration</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Dementia</topic>
    <topic>Pathogenesis</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Movement disorders</topic>
  </subject>
  <subject authority="mesh">
    <topic>Neurodegenerative Diseases</topic>
  </subject>
  <subject authority="mesh">
    <topic>Dementia</topic>
    <topic>pathology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Movement Disorders</topic>
    <topic>pathology</topic>
  </subject>
  <subject>
    <topic>Dementia</topic>
    <topic>Pathogenesis</topic>
  </subject>
  <subject>
    <topic>Dementia</topic>
    <topic>pathology</topic>
  </subject>
  <subject>
    <topic>Movement Disorders</topic>
    <topic>pathology</topic>
  </subject>
  <subject>
    <topic>Nervous system</topic>
    <topic>Degeneration</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>HEALTH &amp; FITNESS</topic>
    <topic>Diseases</topic>
    <topic>Nervous System (incl. Brain)</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Neurology</topic>
  </subject>
  <classification authority="lcc">RC365 .N4527 2011eb</classification>
  <classification authority="ddc" edition="22">616.8</classification>
  <classification authority="nlm">WL 359</classification>
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      <title>Neurodegeneration</title>
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    <originInfo>
      <publisher>Chichester, West Sussex : Wiley-Blackwell, 2011</publisher>
      <edition>2nd ed.</edition>
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    <identifier type="local">(DLC)  2011002976</identifier>
    <identifier type="local">(OCoLC)698580681</identifier>
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  <identifier type="isbn">9781444341256</identifier>
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  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781444341256</identifier>
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    <recordCreationDate encoding="marc">111028</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171116094011.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn758981654</recordIdentifier>
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