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  <titleInfo>
    <title>Chiral drugs : chemistry and biological action</title>
  </titleInfo>
  <name type="personal">
    <namePart>Lin, Guo-Qiang</namePart>
    <namePart type="date">1943-</namePart>
  </name>
  <name type="personal">
    <namePart>You, Qi-Dong.</namePart>
  </name>
  <name type="personal">
    <namePart>Cheng, Jie-Fei.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
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    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
    </place>
    <publisher>Wiley</publisher>
    <dateIssued>©2011</dateIssued>
    <dateIssued encoding="marc">2011</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>1 online resource (x, 456 pages) : illustrations</extent>
  </physicalDescription>
  <abstract>"This book overviews chiral drugs and their impact in the pharmaceutical industry. The chapters detail basics and trends in chiral drug discovery and development, as well as techniques / skills and trends of asymmetric synthesis. The first section introduces the general concept of chirality and its impact on the drug discovery and development. This part includes history of chiral drug development, key technologies for preparation of chiral drugs, and industrial applications of chiral technologies"--Provided by publisher.</abstract>
  <tableOfContents>Overview of chirality and chiral drugs / Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng -- Chiral drugs through asymmetric synthesis / Guo-Quiang Lin and Xing-Wen Sun -- Chiral drugs via biocatalytical approaches / Jianqiang Wang and Wenya Lu -- Chiral resolution / Qi-Dong You -- Fluorine-containing chiral drugs / Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing -- Industrial application of chiral technologies / Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni -- Computation modeling study on mechanism-of-action of chiral drugs / Deping Wang and Eric Gu -- Pharmacology of chiral drugs / Yongge Liu and Xiao-Hui Gu -- Pharmacokinetics of chiral drugs / Hanqing Dong, Xiaochuan Guo and Zengbiao Li -- 10. Toxicology of chiral drugs / Guang Yang and Hai-Zhi Bu -- Representative chiral drugs / Jiangqin Sun, Dingguo Liu and Zhimin Wang.</tableOfContents>
  <note type="statement of responsibility">edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Chiral drugs</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drug development</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Structure-activity relationships (Biochemistry)</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Discovery</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Pharmaceutical Preparations</topic>
    <topic>chemistry</topic>
  </subject>
  <subject authority="mesh">
    <topic>Structure-Activity Relationship</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Drug Guides</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Nursing</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="fast">
    <topic>Chiral drugs</topic>
  </subject>
  <subject authority="fast">
    <topic>Drug development</topic>
  </subject>
  <subject authority="fast">
    <topic>Structure-activity relationships (Biochemistry)</topic>
  </subject>
  <classification authority="lcc">RS429 .C483 2011eb</classification>
  <classification authority="ddc" edition="22">615/.19</classification>
  <classification authority="nlm">QV 744</classification>
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      <title>Chiral drugs</title>
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    <originInfo>
      <publisher>Hoboken, N.J. : Wiley, ©2011</publisher>
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    <identifier type="local">(DLC)  2011002203</identifier>
    <identifier type="local">(OCoLC)700377074</identifier>
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  <identifier type="isbn">9781118075623</identifier>
  <identifier type="isbn">1118075625</identifier>
  <identifier type="isbn">9781118075647</identifier>
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  <identifier type="stock number">323983 MIL</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781118075647</identifier>
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    <recordCreationDate encoding="marc">111017</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171116093622.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn757395650</recordIdentifier>
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