04356cam a2200781Ka 4500 ocn757395650 OCoLC 20171116093622.0 m o d cr cnu---unuuu 111017s2011 njua ob 001 0 eng d 2011002203 9781118075623 (electronic bk.) 1118075625 (electronic bk.) 9781118075647 (electronic bk.) 1118075641 (electronic bk.) 9780470587201 0470587202 9781118075630 9786613239839 AU@ 000049641588 DEBBG BV040070607 DKDLA 820120-katalog:000587916 NZ1 14792724 DEBBG BV043393564 (OCoLC)757395650 (OCoLC)748534078 (OCoLC)756279382 (OCoLC)811493637 (OCoLC)816859636 (OCoLC)961496465 (OCoLC)962718760 (OCoLC)966252129 323983 MIL N$T eng pn N$T YDXCP CDX IDEBK STF E7B MYG OCLCQ UIU OCLCF OCLCQ MHW UKDOC OCLCQ NLGGC EUW EBLCP OCLCQ DEBBG AZK LOA OCLCO OCLCA MAIN RS429 .C483 2011eb QV 744 MED 023000 bisacsh MED 058170 bisacsh MED 071000 bisacsh MED 072000 bisacsh 615/.19 22 Chiral drugs : chemistry and biological action / edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng. [electronic resource] Hoboken, N.J. : Wiley, ©2011. 1 online resource (x, 456 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Overview of chirality and chiral drugs / Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng -- Chiral drugs through asymmetric synthesis / Guo-Quiang Lin and Xing-Wen Sun -- Chiral drugs via biocatalytical approaches / Jianqiang Wang and Wenya Lu -- Chiral resolution / Qi-Dong You -- Fluorine-containing chiral drugs / Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing -- Industrial application of chiral technologies / Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni -- Computation modeling study on mechanism-of-action of chiral drugs / Deping Wang and Eric Gu -- Pharmacology of chiral drugs / Yongge Liu and Xiao-Hui Gu -- Pharmacokinetics of chiral drugs / Hanqing Dong, Xiaochuan Guo and Zengbiao Li -- 10. Toxicology of chiral drugs / Guang Yang and Hai-Zhi Bu -- Representative chiral drugs / Jiangqin Sun, Dingguo Liu and Zhimin Wang. "This book overviews chiral drugs and their impact in the pharmaceutical industry. The chapters detail basics and trends in chiral drug discovery and development, as well as techniques / skills and trends of asymmetric synthesis. The first section introduces the general concept of chirality and its impact on the drug discovery and development. This part includes history of chiral drug development, key technologies for preparation of chiral drugs, and industrial applications of chiral technologies"--Provided by publisher. Print version record. Chiral drugs. Drug development. Structure-activity relationships (Biochemistry) Drug Discovery methods. Pharmaceutical Preparations chemistry. Structure-Activity Relationship. MEDICAL Drug Guides. bisacsh MEDICAL Nursing Pharmacology. bisacsh MEDICAL Pharmacology. bisacsh MEDICAL Pharmacy. bisacsh Chiral drugs. fast (OCoLC)fst00857866 Drug development. fast (OCoLC)fst00898670 Structure-activity relationships (Biochemistry) fast (OCoLC)fst01135737 Electronic books. Electronic books. local Lin, Guo-Qiang, 1943- You, Qi-Dong. Cheng, Jie-Fei. Print version: Chiral drugs. Hoboken, N.J. : Wiley, ©2011 9780470587201 (DLC) 2011002203 (OCoLC)700377074 http://onlinelibrary.wiley.com/book/10.1002/9781118075647 Wiley Online Library ddc BK 205292 205292