Systems biology in drug discovery and development / edited by Daniel L. Young, Seth Michelson. [electronic resource] Young, Daniel L., editor. Michelson, Seth, editor. Drug development. Systems biology. Drug Discovery methods. Models, Biological. Pharmacokinetics. Pharmacological Phenomena. Systems Biology methods. RM301.25 .S97 2011eb 615/.19 22 Includes bibliographical references. Print version record. This is the first comprehensive systems biology book to focus on its applications in drug discovery and development. Using real-world examples, the book shows how systems biology can be used to enhance pharmaceutical research and drug development. It highlights essential components of drug discovery like target identification and validation and complementary systems approaches like text-mining, large multi-context datasets and regression modeling. It also provides models for treatment personalization and methods for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker indentification. Introducing key methods and technical approaches the book addresses the challenges currently facing the drug industry. Hoboken, N.J. : Wiley, 2011. 2011. 2011 Text 1 online resource. http://onlinelibrary.wiley.com/book/10.1002/9781118016435 eng Wiley series on technologies for the pharmaceutical industry Wiley series on technologies for the pharmaceutical industry.