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  <titleInfo>
    <title>Inflammation and allergy drug design</title>
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  <name type="personal">
    <namePart>Izuhara, Kenji.</namePart>
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  <name type="personal">
    <namePart>Holgate, S. T.</namePart>
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  <name type="personal">
    <namePart>Wills-Karp, Marsha.</namePart>
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    <place>
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    <publisher>John Wiley &amp; Sons</publisher>
    <dateIssued>2011</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <tableOfContents>Front Matter -- Novel Anti-Inflammatory Drugs Based on Targeting Lung Dendritic Cells and Airway Epithelial Cells / Bart N Lambrecht, Maud Plantinga, Monique Willart, Hamida Hammad -- Role of Th2 Cells in the Allergic Diathesis / Marsha Wills-karp -- Cells Contributing to the Pathogenesis of Allergic Diseases in the Respiratory Tract. Importance of Th17- and Th1-Associated Responses for the Development of Asthma / Tomohiro Yoshimoto, Hiroko Tsutsui, Kenji Nakanishi -- Regulatory T Cells / Chris Corrigan, Kimuli Ryanna -- A Role for Natural Killer T-Cell Subsets in the Pathogenesis of Various Allergic Disorders / Hiroshi Watarai, Michishige Harada, Mayumi Tamari, Masaru Taniguchi -- Regulatory Roles of B Cells in Allergy and Inflammation / Kiyoshi Takatsu, Masashi Ikutani, Yoshinori Nagai -- Mast Cells / Mindy Tsai, Stephen J Galli -- Eosinophils / Nancy A Lee, Mark V Dahl, Elizabeth A Jacobsen, Sergei I Ochkur -- Basophils in Inflammation and Allergy Drug Design / Donald MacGlashan -- Epithelial Cells / Tillie-Louise Hackett, Stephanie Warner, Dorota Stefanowicz, Darryl Knight -- Fibroblasts / Alastair G Stewart, Lilian Soon, Michael Schuliga -- Airway Smooth Muscle Cells / Andrew J Halayko, Pawan Sharma -- Cytokines Contributing to the Pathogenesis of Allergic Diseases in the Respiratory Tract. Interleukin 4, Interleukin 13, and Interleukin 9 / Kenji Izuhara, Shoichiro Ohta, Hiroshi Shiraishi, Shoichi Suzuki -- Interleukin 3, Interleukin 5, and Granulocyte₆Macrophage Colony-Stimulating Factor / Alba Llop-Guevara, Josip Marcinko, Ramzi Fattouh, Manel Jordana -- Interleukin 15, Interleukin 17, and Interleukin 25 / Hiroshi Nakajima, Itsuo Iwamoto -- Thymic Stromal Lymphopoietin / Kazuhiko Arima, Yong-Jun Liu -- Interleukin 10 / Whitney W Stevens, Larry Borish, John W Steinke -- Tumor Necrosis Factor Alpha / Christopher Brightling, Latifa Chachi, Dhan Desai, Yassine Amrani -- Profibrotic and Angiogenic Factors in Asthma / Neville Berkman, Francesca Levi-Schaffer -- Chemokines / Luis M Teran, Juan R Velazquez -- Epithelial Growth Factors / Yasuhiro Gon, Shu Hashimoto -- Other Mediators Contributing to the Pathogenesis of Allergic Diseases in the Respiratory Tract. Prostanoids / Sarah A Maher, Deborah L Clarke, Maria G Belvisi -- Leukotrienes / Katsuhide Okunishi, Marc Peters-Golden -- Proteases in Allergy / Keisuke Oboki, Hirohisa Saito -- Toll-Like Receptors / Jessica L Allen, Aurelien Trompette, Christopher L Karp -- Index.</tableOfContents>
  <tableOfContents>Novel anti-inflammatory drugs based on targeting lung dentritic cells and airway apithelial cells / Bart Lambrecht [and others] -- Th2 cells / Marsha Wills-Karp -- Importance of Th17 and Th1-associated responses for the development of asthma / Yoshimoto Tomohiro, Tsutsui Hiroko &amp; Nakanishi Kenji -- Regulatory T cells / Christopher Corrigan &amp; Kimuli Ryanna -- A role for invariant NKT cell subsets in the pathogenesis of various allergic disorders / Masaru Taniguchi [and others] -- Regulatory roles of B cells in the allergy and inflammation / Kiyoshi Takatsu, Masashi Ikutani &amp; Yoshinori Nagai -- Mast cells / Steve Galli &amp; Mindy Tsai -- Eosinophils / James Lee, Nancy Lee, Sergei Ochkur &amp; Mark Dahl -- Basophils / Don McGlashan -- Epithelial cells / Darryl Knight [and others] -- Fibroblasts / Alastair Stewart, Lillian Soon &amp; Michael Schuliga -- Smooth muscle cells / Andrew Halayko -- IL-4/IL-13/IL-9 / Kenji Izuhara [and others] -- IL-3/IL-5/GM-CSF / Manuel Jordana ... [et a.]l -- IL-15, IL-17, and IL-25 / Hiroshi Nakajim &amp; Itsuo Iwamoto -- TSLP / Yong-Jun Liu &amp; Kazuhiko Arima -- Interleukin-10 / Larry Borish, Whitney W. Stevens &amp; John W Steinke -- Anti-TNF strategies in experimental asthma and clinical trials : what have we learned? / Christopher Brightling [and others] -- Profibrotic and angiogenic factors in asthma / Francesca Levi- Schaffer &amp; Neville Berkman -- Chemokines / Luis Manuel Teran Juarez &amp; Juan R. Velazquez -- Epithelial growth factors / Shu Hashimoto &amp; Yaihiro Gont -- Prostanoids / Maria Belvisi, Deborah Clarke &amp; Sarah Maher -- Leukotrienes / Mark Peters Golden &amp; Katsuhide Okunishi -- Proteases in allergy / Hirohisa Saito &amp; Keisuke Oboki -- Toll-like receptors / Chris Karp, Jessica L. Allen &amp; Aurelien Trompette.</tableOfContents>
  <note type="statement of responsibility">edited by Kenji Izuhara, Stephen T. Holgate, Marsha Wills-Karp.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Antiallergic agents</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Allergy</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Anti-inflammatory agents</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drugs</topic>
    <topic>Design</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="fast">
    <topic>Allergy</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="fast">
    <topic>Anti-inflammatory agents</topic>
  </subject>
  <subject authority="fast">
    <topic>Antiallergic agents</topic>
  </subject>
  <subject authority="fast">
    <topic>Drugs</topic>
    <topic>Design</topic>
  </subject>
  <subject authority="mesh">
    <topic>Anti-Allergic Agents</topic>
  </subject>
  <subject authority="mesh">
    <topic>Hypersensitivity</topic>
    <topic>drug therapy</topic>
  </subject>
  <subject authority="mesh">
    <topic>Anti-Inflammatory Agents</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Design</topic>
  </subject>
  <classification authority="lcc">RM666.A5 I54 2011</classification>
  <classification authority="ddc" edition="22">615/.7</classification>
  <classification authority="nlm">QV 157</classification>
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      <title>Inflammation and allergy drug design</title>
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