Protein kinases as drug targets / edited by Bert Klebl, Gerhard Müller, and Michael Hamacher. [electronic resource] Müller, Gerhard. Klebl, Bert. Wiley InterScience (Online service) Protein kinases Inhibitors. Antineoplastic agents Development. Protein Kinase Inhibitors therapeutic use. Drug Delivery Systems. Drug Discovery. RM666.E548 P76 2011 615.798 22 Includes bibliographical references and index. Print version record. With Kinase inhibitors being widely seen as the long-sought 'magic bullet' to conquer cancer, this fully comprehensive guide to kinase inhibitor drug development covers the entire drug pipeline from target identification to compound development and clinical application. Volume 1 focuses upon the medicinal chemistry of kinase drugs, from target identification to lead optimization, and contains numerous contributions from large and small pharmaceutical companies. Volume 2 surveys current and future therapeutic application areas for kinase inhibitor drugs, with a strong focus on oncology drugs, as this is the most important therapeutic field for these drugs. In addition, all six currently approved kinase inhibitor drugs (small molecules and antibodies) are described, and their performances in clinical practice are discussed. Weinheim : Wiley-VCH ; Chichester : John Wiley [distributor], ©2011. ©2011. 2011 Text 1 online resource (xxi, 373 pages) : http://onlinelibrary.wiley.com/book/10.1002/9783527633470 eng Methods and principles in medicinal chemistry ; 49 Methods and principles in medicinal chemistry ; 49. Protein kinases as drug targets. Protein kinases as drug targets.