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  <titleInfo>
    <title>Analytical methods for therapeutic drug monitoring and toxicology</title>
  </titleInfo>
  <name type="personal">
    <namePart>Xu, Quanyun A.</namePart>
    <namePart type="date">1961-</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
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  <name type="personal">
    <namePart>Madden, Timothy L.</namePart>
  </name>
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  <genre authority="">Electronic books.</genre>
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    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
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    <publisher>Wiley</publisher>
    <dateIssued>©2011</dateIssued>
    <dateIssued encoding="marc">2011</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>1 online resource (xiv, 502 pages)</extent>
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  <abstract>This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatogr.</abstract>
  <tableOfContents>US adopted name -- Drug category -- Chemical name -- Other names -- Molecular formula -- Molecular weight -- CAS number -- Appearance -- Solubilities -- pKa value(s) -- Individual(s) who developed or published the method -- Drug that was analyzed -- Description of analytical system components -- Description of major operating parameters -- Standard solution preparation -- Sample preparation (dilution, liquid-liquid or SPE extraction, derivatization, etc.) -- Dynamic concentration range of the calibration curve -- Correlation coefficient and linearity -- Coefficient of variation of the assay -- Intraday and interday coefficients of variation of samples -- Limit of detection and limit of quantification -- Interference.</tableOfContents>
  <note type="statement of responsibility">Q. Alan Xu and Timothy L. Madden.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Drugs</topic>
    <topic>Analysis</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drugs</topic>
    <topic>Toxicity testing</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Monitoring</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Toxicology</topic>
    <topic>methods</topic>
  </subject>
  <subject>
    <topic>Medicine</topic>
  </subject>
  <subject>
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Drug Guides</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Nursing</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="fast">
    <topic>Drugs</topic>
    <topic>Analysis</topic>
  </subject>
  <subject authority="fast">
    <topic>Drugs</topic>
    <topic>Toxicity testing</topic>
  </subject>
  <classification authority="lcc">RS189 .X8 2010eb</classification>
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  <classification authority="nlm">WB 330 X85a 2010</classification>
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    <identifier type="local">(DLC)  2010019511</identifier>
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  <identifier type="isbn">9780470909782</identifier>
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