Genotoxic impurities : strategies for identification and control / edited by Andrew Teasdale. [electronic resource] Teasdale, Andrew. Genetic toxicology. Drugs Toxicology. Mutagenicity Tests methods. Drug Toxicity prevention & control. Mutagens adverse effects. Mutagens analysis. Toxicogenetics methods. RA1224.3 .G463 2010eb 616/.042 22 Includes bibliographical references and index. Print version record. This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on safety aspects, including safety tests in vivo and vitro, and data interpretation. T. Hoboken, N.J. : Wiley, ©2010. ©2010. 2010 Text 1 online resource (xii, 428 pages) : http://onlinelibrary.wiley.com/book/10.1002/9780470929377 eng Genotoxic impurities. Genotoxic impurities.