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  <titleInfo>
    <title>RNA interference : application to drug discovery and challenges to pharmaceutical development</title>
  </titleInfo>
  <name type="personal">
    <namePart>Johnson, Paul H.</namePart>
  </name>
  <name type="corporate">
    <namePart>Wiley InterScience (Online service)</namePart>
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  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
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    <place>
      <placeTerm type="text">Hoboken</placeTerm>
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    <publisher>John Wiley &amp; Sons</publisher>
    <dateIssued>©2011</dateIssued>
    <dateIssued encoding="marc">2011</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>xvi, 450 pages : illustrations</extent>
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  <tableOfContents>Frontmatter -- Color Plates -- Biology of RNA Interference. RNA Interference: What is it? / James A Birchler -- Nucleic Acids as Regulatory Molecules / Faqing Huang, C J Yu, Yanlin Guo -- Use of SiRNA Oligonucleotides to Study Gene Function / Kristin A Wiederholt, Adam N Harris -- Genome Scanning by RNA Interference / Roderick L Beijersbergen, Oliver C Steinbach -- Development of SiRNA for Therapeutic Applications. Discovery of New SiRNA Delivery Agents / Paul H Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, Steven C Quay -- SiRNA Delivery Vehicles / Aliasger K Salem, Mark A Behlke -- Interferon, Cytokine Induction, and other Potential Toxicities / Adam Judge, Marjorie Robbins, Ian Maclachlan -- Application of RNA Interference to Viral Diseases / Ralph A Tripp, Stephen Mark Tompkins -- Index.</tableOfContents>
  <note type="statement of responsibility">edited by Paul H. Johnson.</note>
  <note>Includes bibliographical references and index.</note>
  <note>Electronic reproduction. Hoboken, N.J. : Wiley InterScience, 2011. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Jan. 4, 2011). Access may be restricted to users at subscribing institutions.</note>
  <subject authority="lcsh">
    <topic>Drug development</topic>
  </subject>
  <subject authority="lcsh">
    <topic>RNA editing</topic>
  </subject>
  <subject authority="fast">
    <topic>Drug development</topic>
  </subject>
  <subject authority="fast">
    <topic>RNA editing</topic>
  </subject>
  <classification authority="lcc">RM301.25 .R63 2011</classification>
  <classification authority="ddc" edition="22">615/.19</classification>
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  <identifier type="isbn">9780470923733</identifier>
  <identifier type="isbn">0470923733</identifier>
  <identifier type="stock number">10.1002/9780470923733 Wiley InterScience</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9780470923733</identifier>
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