02238nam a22003138a 4500 CR9780511976117 UkCbUP 20170413094209.0 m|||||o||d|||||||| cr|||||||||||| 101011s2011||||enk s ||1 0|eng|d 9780511976117 (ebook) 9780521887212 (hardback) UkCbUP UkCbUP rda 616.99/4 22 Cancer Metastasis : Biologic Basis and Therapeutics / Edited by David Lyden, Danny R. Welch, Bethan Psaila. Cambridge : Cambridge University Press, 2011. 1 online resource (660 pages) : digital, PDF file(s). text txt rdacontent computer c rdamedia online resource cr rdacarrier Title from publisher's bibliographic system (viewed on 09 Oct 2015). Metastasis is responsible for a large burden of morbidity and mortality among cancer patients, and currently few therapies specifically target metastatic disease. Further scientific dissection of the underlying pathways is required to pave the way for new therapeutic targets. This groundbreaking new text comprehensively covers the processes underlying cancer metastasis and the clinical treatment of metastatic disease. Whereas previous volumes have been compendia of laboratory research articles, the internationally renowned authors of this volume have summarized the state-of-the-art research in the metastasis field. A major section covers the cellular and molecular pathways of metastasis and experimental techniques and the systems and models applied in this field. Subsequently, the clinical aspects of the major cancer types are considered, focusing on disease-specific research and therapeutic approaches to metastatic disease. The focus is on novel pathophysiological insights and emerging therapies; future directions for research and unmet clinical needs are also discussed. Lyden, David, editor of compilation. Welch, Danny R. , editor of compilation. Psaila, Bethan, editor of compilation. Print version: 9780521887212 http://dx.doi.org/10.1017/CBO9780511976117 179368 179368