03326cam a22006255i 4500 10818114 BD-DhUL 20160929141512.0 m d cr n 140601s2014 nyua s |||1 0|eng 9781493907151 9781493907144 (print) 9781493907144 10.1007/978-1-4939-0715-1 doi (WaSeSS)ssj0001199639 WaSeSS BD-DhUL BD-DhUL QH301-705 PSA bicssc SCI086000 bisacsh SCI064000 bisacsh 570 23 ELN El-Metwally, Sara. Next generation sequencing technologies and challenges in sequence assembly Sara El-Metwally, Osama M. Ouda, Mohamed Helmy. New York : Springer, 2014. xii, 118 p. : ill. ; 23 cm. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Euro 15.99 Springer briefs in systems biology Includes bibliographical references License restrictions may limit access. The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges. Life sciences. Human genetics. Bioinformatics. Biological models. Life Sciences. Systems Biology. Human Genetics. Bioinformatics. Ouda, Osama M. author. Helmy, Mohamed. author. SpringerLink (Online service) Springer eBooks SpringerLINK ebooks - Biomedical and Life Sciences (2014) SpringerLINK Tracts in Modern Physics Printed edition: 9781493907144 SpringerBriefs in Systems Biology, 2193-4746 ; 7 http://www.columbia.edu/cgi-bin/cul/resolve?clio10818114.001 Full text available from SpringerLINK ebooks - Biomedical and Life Sciences (2014) http://www.columbia.edu/cgi-bin/cul/resolve?clio10818114.002 Full text available from SpringerLINK Tracts in Modern Physics ddc BK 105898 105898 0 0 ddc 0 570_000000000000000_ELN 0 NFIC 183629 DUSL DUSL GEN 2016-08-10 Purchased 570 ELN 497725 2016-09-29 1 2016-09-29 BK 0 0 ddc 0 570_000000000000000_ELN 0 NFIC 183630 DUSL DUSL GEN 2016-08-10 Purchased 570 ELN 497726 2016-09-29 2 2016-09-29 BK