Anticandidal agents / (Record no. 247422)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06254cam a2200601Ma 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn958454824 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190328114816.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr |n||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160916s2016 xx ob 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | IDEBK |
| Language of cataloging | eng |
| Description conventions | pn |
| Transcribing agency | IDEBK |
| Modifying agency | EBLCP |
| -- | STF |
| -- | QCL |
| -- | OCLCQ |
| -- | IDEBK |
| -- | FEM |
| -- | IDB |
| -- | OCLCQ |
| -- | YDX |
| -- | OPELS |
| -- | N$T |
| -- | GZM |
| -- | OCLCO |
| -- | OCLCQ |
| -- | OCLCA |
| -- | U3W |
| -- | MERUC |
| -- | OCLCO |
| -- | D6H |
| -- | CHVBK |
| -- | OCLCQ |
| -- | OCLCO |
| 019 ## - | |
| -- | 958864693 |
| -- | 962435822 |
| -- | 968097371 |
| -- | 969078522 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 012811312X |
| Qualifying information | (ebk) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780128113127 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 0128113111 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780128113110 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)958454824 |
| Canceled/invalid control number | (OCoLC)958864693 |
| -- | (OCoLC)962435822 |
| -- | (OCoLC)968097371 |
| -- | (OCoLC)969078522 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC123.C3 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | WC 470 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | HEA |
| Subject category code subdivision | 039000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 014000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 022000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 112000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 045000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.9/693061 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Kumar, Awanish. |
| 245 10 - TITLE STATEMENT | |
| Title | Anticandidal agents / |
| Medium | [electronic resource] |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | [Place of publication not identified] : |
| Name of producer, publisher, distributor, manufacturer | Elsevier Science, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Source | rda |
| 588 0# - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Print version record. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Front Cover; Anticandidal Agents; Copyright Page; Contents; List of Figures; List of Tables; 1 Introduction; Pathogenesis and Virulence; Genome and Proteome; Genetics; Metabolome; 2 Host-Pathogen Interaction; Morphogenesis; Immune Responses; Delayed-Type Hypersensitivity; Pattern Recognition Receptors; TH Cell Response; 3 Antifungals Used Against Candidiasis; Azoles; Activity and Mechanism of Action; Azole Variants and Their Structure; Ketoconazole; Itraconazole; Fluconazole; Voriconazole; Posoconazole; Ravuconazole; Terconazole; Other Notable Triazoles Include; Polyenes. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Activity and Mechanism of ActionStructure and Variants; Amphotericin B; Nystatin; Natamycin; Echinocandins; Activity and Mechanism of Action; Echinocandins Variants; Caspofungin; Micafungin; Anidulafungin; Pneumocandins; Echinocandin B; Cilofungin; Allylamines; Activity and Mechanism of Action; Variants of Allylamines; Terbinafine; Naftifine; Pyrimidines; Activity and Mechanism of Action; Pyrimidine Variants; 5-FC or Flucytosine; Thiocarbamates and Morpholines; Tolnaftate; Morpholines; Other Inhibitors; Cell Wall Synthesis Inhibitors; Chitin Biosynthesis Inhibitors. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Ergosterol Biosynthesis InhibitorGlucan Synthesis Inhibitors; Novel Inhibitors; Expected Drugs (Compounds in Pipeline); SCY078; Ara-sertaconazole Nitrate; VT-1161; MGCD290; E1210; T-2307; ASP9726; Biafungin (CD101); Isavuconazole; Albaconazole; BQM-Bis [1, 6]quinolizinium 8-Methyl-Salt; Quinazolines; Indole and its Derivatives; Inhibitor Molecules; Sordarins; Tacrolimus; Ascomycin; Milbemycin; Unnarmicin A and Unnarmicin C; Verapamil; Disulfiram; Enniatin B; Trichostatin A; Levofloxacin and Derivatives; Differential Expression of Genes in Response to Drugs; 4 Drug Resistance in Candida. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Emergence of Drug ResistanceSpread of Drug Resistance; Persistence of Drug Resistance; International Data; National Data; Multidrug Resistance; 5 Multidrug Resistance and Transporters; Overview of Efflux Pumps; ABC Transporters; MFS Transporters; Fungal Efflux-Mediated Drug Resistance; Overcoming Efflux-Mediated Drug Resistance; 6 Potential Anticandidal Targets; Surface Targets; ABC Transporters; Key Factors; MFS Transporters; QDR; Cellular Targets; Cross Talk; 7 Drug Development Strategies; In Vitro Based; Biochemical Estimation; Toxicity Assay; Drug Susceptibility; Effects on Biofilm. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | In Vivo BasedBioavailability; Toxicity; ADME; Absorption and Distribution; Metabolism and Excretion; Pharmacokinetics and Pharmacodynamics; In Silico Based; Computer-Aided Drug Discovery and Development; Molecular Docking; Molecular Modeling; Virtual Screening; Quantitative Structured Activity Relationship; 8 Conclusion; Abbreviations; Bibliography; Back Cover. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications. In this compilation, users will find a comprehensive view on overcoming resistance in anticandidal drugs, along with information on novel molecules. Candida albicans is an opportunistic pathogenic fungus responsible for life threating invasive and nosocomial infections across the globe. Candidiasis is a major cause of morbidity among immunocompromised patients. Infections caused by non-albicans candida like C. glabrata, C. parapsilosis, and C. tropicalis have also imposed a serious threat in the last few decades. Current treatment of candidiasis relies primarily on antifungal agents broadly categorized as azoles, polyenes, echinocandins, allylamines, and pyrimidines. Lately, antifungal resistance has emerged to be an obstruction of current treatment regime. A number of reasons are described in detail. Understanding the mechanisms of resistance is crucial for developing strategies for overcoming the hindrance in current therapeutics. Presents a complete understanding of candida resistance to help in the development of therapeutic expansion and novel drugs Provides thorough information on candida drug resistance and its remedial implications Covers crucial mechanisms of resistance that will help develop strategies for overcoming the hindrance in current therapeutics. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Candidiasis |
| General subdivision | Chemotherapy. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | HEALTH & FITNESS |
| General subdivision | Diseases |
| -- | General. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Clinical Medicine. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Diseases. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Evidence-Based Medicine. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Internal Medicine. |
| Source of heading or term | bisacsh |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Candidiasis |
| General subdivision | therapy. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Kumar, Awanish. |
| Title | Anticandidal agents. |
| Place, publisher, and date of publication | San Diego, CA : Academic Press, [2016], �2017 |
| International Standard Book Number | 9780128113110 |
| -- | 0128113111 |
| Record control number | (OCoLC)953708342 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | ScienceDirect |
| Uniform Resource Identifier | http://www.sciencedirect.com/science/book/9780128113110 |
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