Fundamentals of toxicology : essential concepts and applications / (Record no. 247408)
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| control field | ocn957589957 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190328114816.0 |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160901s2016 enk ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | N$T |
| Language of cataloging | eng |
| Description conventions | rda |
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| Transcribing agency | N$T |
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| 019 ## - | |
| -- | 961250225 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780128054031 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0128054034 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780128054260 |
| Qualifying information | (print) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 0128054263 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)957589957 |
| Canceled/invalid control number | (OCoLC)961250225 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RA1211 |
| 060 00 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | 2016 J-286 |
| 060 10 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | QV 600 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 071000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.9 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Gupta, P. K. |
| Fuller form of name | (Pawan K.), |
| Dates associated with a name | 1943- |
| Relator term | author. |
| 245 10 - TITLE STATEMENT | |
| Title | Fundamentals of toxicology : essential concepts and applications / |
| Medium | [electronic resource] |
| Statement of responsibility, etc. | P.K. Gupta. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | London, United Kingdom : |
| Name of producer, publisher, distributor, manufacturer | Academic Press is an imprint of Elsevier, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 588 0# - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Online resource; title from PDF title page (ScienceDirect, viewed September 12, 2016). |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Front Cover; Fundamentals of Toxicology; Copyright Page; Contents; About the Author; Foreword; Preface; Unit I; 1 Introduction and historical background; 1.1 Introduction; 1.2 Historical Background; 1.2.1 Antiquity; 1.2.2 Middle Ages; 1.2.3 Age of Enlightenment; 1.3 Modern Toxicology; 1.3.1 After World War II; 2 Definitions and scope of toxicology; 2.1 Definitions; 2.2 Sub-disciplines of Toxicology; 2.3 Toxicant and Types of Toxicants; 2.4 Toxicity and Toxic Effects; 2.4.1 Toxicity in Relation to Frequency and Duration of Exposure. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2.4.2 Toxicity in Relation to Time of Development and Duration of Induced Effects2.5 Dose and Related Terms; 2.6 Other Common Terms; 2.7 Sources of Poisoning; 2.7.1 Accidental Poisoning; 2.7.2 Malicious Poisoning; 2.7.3 Occupational Exposure; 2.8 Duration and Frequency of Exposure; 3 Classification of poisons/toxicants; 3.1 Introduction; 3.2 Classification of Poisons; 3.3 Actions of Poisons; 4 Factors affecting toxicity; 4.1 Introduction; 4.2 Factors Affecting Toxicity; 4.2.1 Host Factors; 4.2.2 Factors Related to the Toxicant or Associated With Xenobiotics; 4.2.3 Environmental Conditions. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 5 Natural laws concerning toxicology5.1 Introduction; 5.2 Tolerance; 5.3 Dose; 5.4 Time Action Curves; 5.5 Dose-Response Relationship; 5.5.1 Graded or Gradual Dose-Response Relationship; 5.5.2 Quantal or All-or-None Dose-Response Relationship; 5.6 Statistical Concept of Toxicity; 5.7 Variables of Dose-Response Curve; 5.8 Frequently Used Terms for Safety Evaluation of Drugs; 5.9 Interaction With Receptors; 5.10 Types of Xenobiotics; 5.11 Xenobiotic/Drug Interaction; 5.12 Nature and Extent of Toxicity Testing; 6 Hazard and risk assessment; 6.1 Introduction; 6.2 Risk Assessment Approach. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 6.2.1 Preliminary Evaluation6.2.2 Toxicity Assessment; 6.2.3 Exposure Assessment; 6.3 Conclusion; Unit II; 7 Absorption, distribution, and excretion of toxicants; 7.1 Introduction; 7.2 Translocation of Xenobiotics Across Membranes; 7.2.1 Membrane Permeability; 7.2.2 Mechanism of Chemical Transfer; 7.2.3 Processes of Transport; 7.2.3.1 Passive transport; 7.2.3.2 Specialized active transport; 7.2.3.3 Additional transport processes; 7.3 Absorption; 7.3.1 Gastrointestinal Absorption; 7.3.2 Skin Absorption; 7.3.3 Lungs Absorption; 7.3.4 Parenteral Administration; 7.4 Distribution. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 7.4.1 Tissue Permeability Barriers7.4.2 Transfer Across Other Membranes; 7.4.3 Factors Affecting Distribution and Tissue Retention; 7.4.4 Binding to Biological Macromolecules and Toxic Effects; 7.4.5 Redistribution; 7.5 Excretion; 7.5.1 Renal Excretion; 7.5.2 Biliary Excretion; 7.5.3 Gastrointestinal Tract; 7.5.4 Expired Air; 7.5.5 Sweat; 7.5.6 Saliva; 7.5.7 Milk; 7.5.8 Vaginal Secretions; 7.5.9 Other Routes; 8 Biotransformation; 8.1 Introduction; 8.2 Functions of Biotransformation; 8.3 Xenobiotic Metabolizing Enzymes; 8.4 Pathways of Biotransformation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Toxicology. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Pharmacology. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Toxicology. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst01153364 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Toxicology. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Gupta, P.K. (Pawan K.), 1943- |
| Title | Fundamentals of toxicology. |
| Place, publisher, and date of publication | London, United Kingdom : Academic Press is an imprint of Elsevier, 2016 |
| International Standard Book Number | 9780128054260 |
| -- | 0128054263 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | ScienceDirect |
| Uniform Resource Identifier | http://www.sciencedirect.com/science/book/9780128054260 |
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