Molecular biology of B cells / (Record no. 246969)
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| fixed length control field | 06360cam a2200769Ii 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn893332893 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190328114809.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu---unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 141018s2015 enka ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EBLCP |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | EBLCP |
| Modifying agency | N$T |
| -- | GZM |
| -- | YDXCP |
| -- | OCLCO |
| -- | UIU |
| -- | OCLCQ |
| -- | OCLCO |
| -- | N$T |
| -- | COO |
| -- | TPH |
| -- | DEBSZ |
| -- | ITD |
| -- | OCLCF |
| -- | UAB |
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| -- | MERER |
| -- | OCLCO |
| -- | OCLCQ |
| -- | VGM |
| -- | OCLCO |
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| -- | MERUC |
| -- | D6H |
| -- | OCLCO |
| -- | OCLCQ |
| -- | AU@ |
| -- | OCLCQ |
| -- | UBY |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780123984906 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0123984904 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0123979331 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780123979339 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780123979339 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)893332893 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QR185.6 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | Online Book |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | HEA |
| Subject category code subdivision | 039000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 014000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 022000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 112000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 045000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.07 |
| -- | 616.0798 |
| 245 00 - TITLE STATEMENT | |
| Title | Molecular biology of B cells / |
| Medium | [electronic resource] |
| Statement of responsibility, etc. | edited by Frederick W. Alt, Tasuku Honjo, Andreas Radbruch, Michael Reth. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 2nd ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | London : |
| Name of producer, publisher, distributor, manufacturer | Elsevier Science, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2015. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xxiii 563 pages) : |
| Other physical details | color illustrations |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 588 0# - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Online resource; title from PDF title page (ScienceDirect, viewed on November 6, 2014). |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with update. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Front Cover; Molecular Biology of B Cells; Copyright; Dedication; Contents; Preface; Contributors; Chapter 1 -- The Structure and Regulation of the Immunoglobulin Loci; 1. INTRODUCTION; 2. GENOMIC ORGANIZATION OF THE MOUSE IMMUNOGLOBULIN HEAVY CHAIN LOCUS; 3. GENOMIC ORGANIZATION OF THE MOUSE IMMUNOGLOBULIN KAPPA LIGHT CHAIN LOCUS; 4. GENOMIC ORGANIZATION OF THE MOUSE IMMUNOGLOBULIN LAMBDA LIGHT CHAIN LOCUS; 5. B CELL DEVELOPMENT AND REGULATION OF V(D)J RECOMBINATION; 6. JUNCTIONAL DIVERSITY; 7. COMBINATORIAL DIVERSITY; 8. NONCODING TRANSCRIPTION AND IMMUNOGLOBULIN LOCUS REARRANGEMENT. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 9. THE PROCESS OF DH-JH RECOMBINATION10. EPIGENETICS AND IMMUNOGLOBULIN LOCUS REARRANGEMENT; 11. INSULATORS AND IMMUNOGLOBULIN LOCUS REARRANGEMENT; 12. 3D STRUCTURE AND COMPACTION OF THE IMMUNOGLOBULIN HEAVY CHAIN LOCUS; 13. CONCLUSION; REFERENCES; Chapter 2 -- The Mechanism of V(D)J Recombination; 1. OVERVIEW; 2. ANTIGEN RECEPTOR GENE ASSEMBLY; 3. RECOMBINATION SIGNAL SEQUENCES; 4. BIOCHEMISTRY OF V(D)J CLEAVAGE; 5. RAG1 AND RAG2; 6. A ROLE FOR HMGB1 IN V(D)J RECOMBINATION; 7. RECOMBINATION COMPLEXES: ANALYSIS OF STOICHIOMETRY AND ORGANIZATION. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 8. V(D)J RECOMBINATION IS TIGHTLY REGULATED DURING LYMPHOCYTE DEVELOPMENT9. ACCESSIBILITY MODEL OF REGULATION; 10. OVERVIEW OF CHROMATIN STRUCTURE; 11. REGULATION BY NUCLEOSOME STRUCTURE AND HISTONE ACETYLATION; 12. REGULATION BY HISTONE METHYLATION; 13. HOW IS THE CHROMATIN STRUCTURE OF ANTIGEN RECEPTOR LOCI DEVELOPMENTALLY REGULATED?; 14. ADDITIONAL LAYERS OF REGULATION; 15. REGULATION OF V(D)J RECOMBINATION: SUMMARY; 16. ONCOGENIC LESIONS IN LYMPHOID NEOPLASMS: THE PRICE OF A DIVERSE ANTIGEN RECEPTOR REPERTOIRE; 17. PROPOSED MECHANISMS UNDERLYING RAG-MEDIATED GENOMIC LESIONS. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 18. REGULATORY CONTROLS PROPOSED TO SUPPRESS RAG-MEDIATED GENOMIC INSTABILITY19. V(D)J RECOMBINATION ERRORS AS PATHOGENIC LESIONS IN LYMPHOID NEOPLASMS: SUMMARY; REFERENCES; Chapter 3 -- Transcriptional Regulation of Early B Cell Development; 1. PU. 1 SETS THE STAGE FOR LYMPHOID AND MYELOID DEVELOPMENT; 2. LINEAGE PRIMING IN LYMPHOID PROGENITORS BY IKAROS; 3. E2A REGULATES THE CHROMATIN LANDSCAPE TO PROMOTE GENE EXPRESSION IN B CELL DEVELOPMENT; 4. E2A IS INHIBITED BY ID PROTEINS; 5. INTERLEUKIN-7/STAT5 SIGNALING PROVIDES AN EARLY SIGNAL FOR B CELL LINEAGE SPECIFICATION. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 6. EARLY B CELL FACTOR: CENTRAL COORDINATOR OF B CELL DEVELOPMENT7. COLLABORATION BETWEEN EBF1 AND FOXO1; 8. REGULATION OF THE B CELL-SPECIFIC PROGRAM BY PAX5; 9. REGULATION OF B LINEAGE COMMITMENT; 10. CONCLUSION; ACKNOWLEDGMENT; REFERENCES; Chapter 4 -- Relationships among B Cell Populations Revealed by Global Gene Analysis; 1. INTRODUCTION; 2. GENE PROFILE CHANGES WITH B CELL MATURATION SUGGEST AN ORDERING OF TRANSITIONAL STAGES; 3. DISTINCTIONS IN GENE NETWORKS ACTIVATED IN MATURE B CELL POPULATIONS. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Molecular immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | B cells. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | B cells |
| General subdivision | Differentiation |
| -- | Molecular aspects. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunoglobulins. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunoglobulin genes. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | B-Lymphocytes. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunoglobulins. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cell Differentiation |
| General subdivision | physiology. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | HEALTH & FITNESS |
| General subdivision | Diseases |
| -- | General. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Clinical Medicine. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Diseases. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Evidence-Based Medicine. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Internal Medicine. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | B cells. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst00824789 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | B cells |
| General subdivision | Differentiation |
| -- | Molecular aspects. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst00824791 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunoglobulin genes. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst00967959 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunoglobulins. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst00967961 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Molecular immunology. |
| Source of heading or term | fast |
| Authority record control number | (OCoLC)fst01024811 |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Honj�o, Tasuku, |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Reth, Michael, |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Radbruch, A. |
| Fuller form of name | (Andreas), |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alt, Frederick W., |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Title | Molecular biology of B cells. |
| Place, publisher, and date of publication | Boston, Massachusetts : Elsevier, [2015] |
| International Standard Book Number | 9780123979339 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | ScienceDirect |
| Uniform Resource Identifier | http://www.sciencedirect.com/science/book/9780123979339 |
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