Foye's principles of medicinal chemistry /
Principles of medicinal chemistry
[edited by] David A. Williams, Thomas L. Lemke.
- 5th ed.
- Philadelphia : Lippincott Williams & Wilkins, c2002.
- xii, 1114 p. : ill. ; 29 cm.
Includes bibliographical references and indexes.
Introduction: Origins of Medicinal Chemistry / Principles of Drug Discovery -- Overview: Drug Design and Development: A Perspective / Natural Products / Drug Design and Relationship of Functional Groups to Pharmacologic Activity / Molecular Modeling and Drug Design / Receptors and Drug Action / Drug Design Through Enzyme Inhibition / Peptide and Protein Drugs / Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics / Drug Metabolism / U.S. Drug Regulation: An Overview / Pharmacodynamic Agents -- Overview: Drug Receptors: A Perspective / Drugs Affecting Cholinergic Neurotransmission / William O. Foye -- Michael Williams. Alice M. Clark. James J. Knittel and Robin M. Zavod. Eric Billings. Timothy J. Maher and David A. Johnson. Stephen G. Kerr. Michael Mokotoff. Sunil Jambhekar. David A. Williams. Douglas J. Pisano -- David J. Triggle. Danny L. Lattin and E. Kim Fifer. Pt. I. 1. 2. 3. 4. 5. 6. 7. 8. 9. Pt. II. 10. Drugs Affecting Adrenergic Neurotransmission / Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission / Local Anesthetics / Volatile Anesthetics / Hypnotics / Antiseizure Drugs / Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents / Hallucinogens, Stimulants, and Related Drugs of Abuse / Opioid Analgesics / Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents / Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs / Diuretics / Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers / Robert Griffith. Richard A. Glennon and Malgorzata Dukat. Matthias C. Lu. Timothy J. Maher. William Soine. Barbara W. Leduc. Raymond G. Booth and John L. Neumeyer. Richard A. Glennon. David S. Fries. Raymond G. Booth and John L. Neumeyer. Ahmed S. Mehanna. Gary O. Rankin. Marc W. Harrold. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. Central and Peripheral Sympatholytics and Vasodilators / Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis / Antithrombotics, Thrombolytics, Coagulants and Plasma Extenders / Insulin and Oral Hypoglycemic Drugs / Adrenocorticoids / Estrogen, Progestins and Androgens / Thyroid Function and Thyroid Drugs / Calcium Homeostasis / Nonsteroidal Anti-Inflammatory Agents / Antihistamines and Related Antiallergic and Antiulcer Agents / Antibiotics and Antimicrobial Agents / Antiparasitic Agents / Antifungal Drugs / Antimycobacterial Agents / David A. Williams. Marc W. Harrold. Robert B. Palmer. Robert A. Wiley. Duane D. Miller, Robert W. Brueggemeier and James T. Dalton. Robert W. Brueggemeier, Duane D. Miller and James T. Dalton. Ali R. Banijamali. Robin M. Zavod. Ronald F. Borne. Wendel L. Nelson. Lester A. Mitscher. Thomas L. Lemke. Robert Griffith and Timothy Tracy. Thomas L. Lemke. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. Cancer and Cancer Chemotherapy / Antiviral Agents and Protease Inhibitors / Recent Advances in Drug Discovery. Pharmaceutical Biotechnology / Gene Therapy / Antisense Therapeutic Agents / Selective Estrogen Receptor Modulators / pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases; pH Values for Tissue Fluids / Patrick S. Callery and Peter M. Gannett. Manohar L. Sethi -- Robert D. Sindelar. Ronald E. Reid. Marilyn K. Speedie. V. Craig Jordan -- David A. Williams. 38. 39. Pt. III. 40. 41. 42. 43.
0683307371
2001050327
Pharmaceutical chemistry.
Chemistry, Pharmaceutical.
RS403 / .P75 2002
615.19 / WIF
Includes bibliographical references and indexes.
Introduction: Origins of Medicinal Chemistry / Principles of Drug Discovery -- Overview: Drug Design and Development: A Perspective / Natural Products / Drug Design and Relationship of Functional Groups to Pharmacologic Activity / Molecular Modeling and Drug Design / Receptors and Drug Action / Drug Design Through Enzyme Inhibition / Peptide and Protein Drugs / Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics / Drug Metabolism / U.S. Drug Regulation: An Overview / Pharmacodynamic Agents -- Overview: Drug Receptors: A Perspective / Drugs Affecting Cholinergic Neurotransmission / William O. Foye -- Michael Williams. Alice M. Clark. James J. Knittel and Robin M. Zavod. Eric Billings. Timothy J. Maher and David A. Johnson. Stephen G. Kerr. Michael Mokotoff. Sunil Jambhekar. David A. Williams. Douglas J. Pisano -- David J. Triggle. Danny L. Lattin and E. Kim Fifer. Pt. I. 1. 2. 3. 4. 5. 6. 7. 8. 9. Pt. II. 10. Drugs Affecting Adrenergic Neurotransmission / Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission / Local Anesthetics / Volatile Anesthetics / Hypnotics / Antiseizure Drugs / Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents / Hallucinogens, Stimulants, and Related Drugs of Abuse / Opioid Analgesics / Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents / Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs / Diuretics / Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers / Robert Griffith. Richard A. Glennon and Malgorzata Dukat. Matthias C. Lu. Timothy J. Maher. William Soine. Barbara W. Leduc. Raymond G. Booth and John L. Neumeyer. Richard A. Glennon. David S. Fries. Raymond G. Booth and John L. Neumeyer. Ahmed S. Mehanna. Gary O. Rankin. Marc W. Harrold. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. Central and Peripheral Sympatholytics and Vasodilators / Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis / Antithrombotics, Thrombolytics, Coagulants and Plasma Extenders / Insulin and Oral Hypoglycemic Drugs / Adrenocorticoids / Estrogen, Progestins and Androgens / Thyroid Function and Thyroid Drugs / Calcium Homeostasis / Nonsteroidal Anti-Inflammatory Agents / Antihistamines and Related Antiallergic and Antiulcer Agents / Antibiotics and Antimicrobial Agents / Antiparasitic Agents / Antifungal Drugs / Antimycobacterial Agents / David A. Williams. Marc W. Harrold. Robert B. Palmer. Robert A. Wiley. Duane D. Miller, Robert W. Brueggemeier and James T. Dalton. Robert W. Brueggemeier, Duane D. Miller and James T. Dalton. Ali R. Banijamali. Robin M. Zavod. Ronald F. Borne. Wendel L. Nelson. Lester A. Mitscher. Thomas L. Lemke. Robert Griffith and Timothy Tracy. Thomas L. Lemke. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. Cancer and Cancer Chemotherapy / Antiviral Agents and Protease Inhibitors / Recent Advances in Drug Discovery. Pharmaceutical Biotechnology / Gene Therapy / Antisense Therapeutic Agents / Selective Estrogen Receptor Modulators / pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases; pH Values for Tissue Fluids / Patrick S. Callery and Peter M. Gannett. Manohar L. Sethi -- Robert D. Sindelar. Ronald E. Reid. Marilyn K. Speedie. V. Craig Jordan -- David A. Williams. 38. 39. Pt. III. 40. 41. 42. 43.
0683307371
2001050327
Pharmaceutical chemistry.
Chemistry, Pharmaceutical.
RS403 / .P75 2002
615.19 / WIF